Anti-NUMB Antibody
Catalog No : IGX-46248
237.00€
175.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage. | ||
|---|---|---|---|
| Other names | Protein numb homolog, h-Numb, Protein S171, NUMB, C14orf41 | ||
| Cellular localization | Membrane, Peripheral Membrane | ||
| Research area | Neuroscience | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | P49757 | ||
| Product name | Anti-NUMB Antibody | ||
|---|---|---|---|
| Catalog No | IGX-46248 | ||
| Supplier’s Catalog No | IGX-46248 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human, Mouse | ||
| Applications | ELISA, WB | ||
| Recommended dilutions | WB: 1:1000-1:5000 | ||
| Molecular weight | Predicted band size: 71 KDa. Observed band size: 71 KDa. | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Protein numb homolog protein (532-651AA) | ||
| Specificity | NUMB antibody detects endogenous level of NUMB protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | Concentration can vary between different batches. | ||
| Storage buffer | Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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