Anti-GRIN2D Antibody
Catalog No : IGX-46256
237.00€
175.00€
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| Description | Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg2+ (PMID:9489750, PMID:27616483, PMID:26875626, PMID:28126851). Sensitivity to glutamate and channel kinetics depend on the subunit composition (PMID:9489750). | ||
|---|---|---|---|
| Other names | Glutamate receptor ionotropic, NMDA 2D, GluN2D, EB11, Glutamate [NMDA] receptor subunit epsilon-4, N-methyl D-aspartate receptor subtype 2D, NMDAR2D, NR2D, GRIN2D, GluN2D NMDAR2D | ||
| Cellular localization | Plasma Membrane, Multi-Pass Membrane, Postsynaptic Membrane | ||
| Research area | Neuroscience | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | O15399 | ||
| Product name | Anti-GRIN2D Antibody | ||
|---|---|---|---|
| Catalog No | IGX-46256 | ||
| Supplier’s Catalog No | IGX-46256 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, WB | ||
| Recommended dilutions | WB: 1:1000-1:5000 | ||
| Molecular weight | Predicted band size: 144 KDa. Observed band size: 144 KDa. | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Glutamate receptor ionotropic, NMDA 2D protein (330-480AA) | ||
| Specificity | GRIN2D antibody detects endogenous level of GRIN2D protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | Concentration can vary between different batches. | ||
| Storage buffer | Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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