Anti-EXT1 / Exostosin-1 Antibody
Catalog No : IGX-46265
262.00€
188.00€
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| Description | Glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor. Required for the exosomal release of SDCBP, CD63 and syndecan (PMID:22660413). | ||
|---|---|---|---|
| Other names | Exostosin-1, EC 2.4.1.224, EC 2.4.1.225, Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase, Multiple exostoses protein 1, Putative tumor suppressor protein EXT1, EXT1 | ||
| Cellular localization | Endoplasmic Reticulum, Endoplasmic Reticulum Membrane, Single-Pass Type Ii Membrane, Golgi Apparatus, Golgi Apparatus Membrane | ||
| Research area | Signal Transduction | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q16394 | ||
| Product name | Anti-EXT1 / Exostosin-1 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-46265 | ||
| Supplier’s Catalog No | IGX-46265 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, WB | ||
| Recommended dilutions | WB: 1:1000-1:5000 | ||
| Molecular weight | Predicted band size: 87 KDa. Observed band size: 87 KDa. | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Exostosin-1 protein (28-171AA) | ||
| Specificity | EXT1 antibody detects endogenous level of EXT1 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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