Anti-APH1B Antibody
Catalog No : IGX-46331
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (amyloid-beta precursor protein). It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex. Probably present in a minority of gamma-secretase complexes compared to APH1A. | ||
|---|---|---|---|
| Other names | Gamma-secretase subunit APH-1B, APH-1b, Aph-1beta, Presenilin-stabilization factor-like, APH1B, PSFL | ||
| Cellular localization | Membrane, Multi-Pass Membrane | ||
| Research area | Neuroscience | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q8WW43 | ||
| Product name | Anti-APH1B Antibody | ||
|---|---|---|---|
| Catalog No | IGX-46331 | ||
| Supplier’s Catalog No | IGX-46331 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, WB | ||
| Recommended dilutions | WB: 1:1000-1:5000 | ||
| Molecular weight | Predicted band size: 29 KDa. Observed band size: 29 KDa. | ||
| Conjugate | Unconjugated | ||
| Immunogen | Peptide sequence from Human Gamma-secretase subunit APH-1B protein (93-110AA) | ||
| Specificity | APH1B antibody detects endogenous level of APH1B protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | Concentration can vary between different batches. | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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