Anti-AVIL / Advillin Antibody (p92)
Catalog No : IGX-46334
262.00€
188.00€
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| Description | Ca2+-regulated actin-binding protein which plays an important role in actin bundling (PMID:29058690). May have a unique function in the morphogenesis of neuronal cells which form ganglia. Required for SREC1-mediated regulation of neurite-like outgrowth. Plays a role in regenerative sensory axon outgrowth and remodeling processes after peripheral injury in neonates. Involved in the formation of long fine actin-containing filopodia-like structures in fibroblast. Plays a role in ciliogenesis. In podocytes, controls lamellipodia formation through the regulation of EGF-induced diacylglycerol generation by PLCE1 and ARP2/3 complex assembly (PMID:29058690). | ||
|---|---|---|---|
| Other names | Advillin, p92, AVIL | ||
| Cellular localization | Cytoskeleton, Lamellipodium, Focal Adhesion, Neuron Projection, Axon | ||
| Research area | Neuroscience | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | O75366 | ||
| Product name | Anti-AVIL / Advillin Antibody (p92) | ||
|---|---|---|---|
| Catalog No | IGX-46334 | ||
| Supplier’s Catalog No | IGX-46334 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, WB | ||
| Recommended dilutions | WB: 1:1000-1:5000 | ||
| Molecular weight | Predicted band size: 93 KDa. Observed band size: 93 KDa. | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Advillin protein (623-819AA) | ||
| Specificity | AVIL antibody detects endogenous level of AVIL protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | Concentration can vary between different batches. | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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