Anti-ENPP7 Antibody
Catalog No : IGX-46355
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Choline-specific phosphodiesterase that hydrolyzes sphingomyelin releasing the ceramide and phosphocholine and therefore is involved in sphingomyelin digestion, ceramide formation, and fatty acid (FA) absorption in the gastrointestinal tract (PMID:12885774, PMID:12671034, PMID:15205117, PMID:16255717, PMID:28292932). Has also phospholipase C activity and can also cleave phosphocholine from palmitoyl lyso-phosphatidylcholine and platelet-activating factor (PAF) leading to its inactivation (PMID:16255717, PMID:12885774). Does not have nucleotide pyrophosphatase activity (PMID:12885774). May promote cholesterol absorption by affecting the levels of sphingomyelin derived from either diet or endogenous sources, in the intestinal lumen . | ||
|---|---|---|---|
| Other names | Ectonucleotide pyrophosphatase/phosphodiesterase family member 7, E-NPP 7, NPP-7, EC 3.1.4.12, Alkaline sphingomyelin phosphodiesterase, Intestinal alkaline sphingomyelinase, Alk-SMase, ENPP7 | ||
| Cellular localization | Plasma Membrane, Membrane, Single-Pass Type I Membrane | ||
| Research area | Cell Biology | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q6UWV6 | ||
| Product name | Anti-ENPP7 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-46355 | ||
| Supplier’s Catalog No | IGX-46355 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human, Mouse | ||
| Applications | ELISA, WB, IF | ||
| Recommended dilutions | WB: 1:1000-1:5000, IF: 1:200-1:500 | ||
| Molecular weight | Predicted band size: 52 KDa. Observed band size: 52 KDa. | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 protein (22-216AA) | ||
| Specificity | ENPP7 antibody detects endogenous level of ENPP7 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | Concentration can vary between different batches. | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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