Anti-MX1 Antibody
Catalog No : IGX-47543
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Interferon-induced dynamin-like GTPase with antiviral activity against a wide range of RNA viruses and some DNA viruses. Its target viruses include negative-stranded RNA viruses and HBV through binding and inactivation of their ribonucleocapsid. May also antagonize reoviridae and asfarviridae replication. Inhibits thogoto virus (THOV) replication by preventing the nuclear import of viral nucleocapsids. Inhibits La Crosse virus (LACV) replication by sequestering viral nucleoprotein in perinuclear complexes, preventing genome amplification, budding, and egress. Inhibits influenza A virus (IAV) replication by decreasing or delaying NP synthesis and by blocking endocytic traffic of incoming virus particles. Enhances ER stress-mediated cell death after influenza virus infection. May regulate the calcium channel activity of TRPCs. | ||
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| Other names | Interferon-induced GTP-binding protein Mx1, Interferon-induced protein p78, IFI-78K, Interferon-regulated resistance GTP-binding protein MxA, Myxoma resistance protein 1, Myxovirus resistance protein 1, [Cleaved into: Interferon-induced GTP-binding protein Mx1, N-terminally processed], MX1 | ||
| Cellular localization | Endoplasmic Reticulum Membrane, Peripheral Membrane, , Cytoplasm, Perinuclear Region, Nucleus, Cytoplasm | ||
| Research area | Microbiology | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | P20591 | ||
| Product name | Anti-MX1 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-47543 | ||
| Supplier’s Catalog No | IGX-47543 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human, Mouse | ||
| Applications | ELISA, WB, IHC, IF, IP | ||
| Recommended dilutions | WB: 1:1000-1:5000, IHC: 1:20-1:200, IF: 1:50-1:200, IP: 1:200-1:2000 | ||
| Molecular weight | Predicted band size: 76, 56 KDa. Observed band size: 76 KDa. | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Interferon-induced GTP-binding protein Mx1 protein (7-172AA) | ||
| Specificity | MX1 antibody detects endogenous level of MX1 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
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| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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