Anti-CERS3 / Ceramide synthase 3 Antibody
Catalog No : IGX-49475
262.00€
188.00€
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| Description | Ceramide synthase that catalyzes formation of ceramide from sphinganine and acyl-CoA substrates, with high selectivity toward very-long (C22:0-C24:0) and ultra long chain (more than C26:0) as acyl donor (PMID:17977534, PMID:22038835, PMID:26887952). It is crucial for the synthesis of ultra long-chain ceramides in the epidermis, to maintain epidermal lipid homeostasis and terminal. differentiation (PMID:23754960). | ||
|---|---|---|---|
| Other names | Ceramide synthase 3, CerS3, EC 2.3.1.24, Dihydroceramide synthase 3, LAG1 longevity assurance homolog 3, CERS3, LASS3 | ||
| Cellular localization | Endoplasmic Reticulum Membrane, Multi-Pass Membrane | ||
| Research area | Signal Transduction | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q8IU89 | ||
| Product name | Anti-CERS3 / Ceramide synthase 3 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-49475 | ||
| Supplier’s Catalog No | IGX-49475 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human, Mouse | ||
| Applications | ELISA, WB | ||
| Recommended dilutions | WB: 1:500-1:5000 | ||
| Molecular weight | Predicted band size: 47 KDa. Observed band size: 47 KDa. | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Ceramide synthase 3 protein (59-134AA) | ||
| Specificity | CERS3 antibody detects endogenous level of CERS3 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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