Anti-CD9 Antibody
Catalog No : IGX-59266
282.00€
201.00€
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| Description | Integral membrane protein associated with integrins, which regulates different processes, such as sperm-egg fusion, platelet activation and aggregation, and cell adhesion (PMID:8478605, PMID:14575715, PMID:18541721). Present at the cell surface of oocytes and plays a key role in sperm-egg fusion, possibly by organizing multiprotein complexes and the morphology of the membrane required for the fusion . In myoblasts, associates with CD81 and PTGFRN and inhibits myotube fusion during muscle regeneration . In macrophages, associates with CD81 and beta-1 and beta-2 integrins, and prevents macrophage fusion into multinucleated giant cells specialized in ingesting complement-opsonized large particles (PMID:12796480). Also prevents the fusion between mononuclear cell progenitors into osteoclasts in charge of bone resorption . Acts as a receptor for PSG17 . Involved in platelet activation and aggregation (PMID:18541721). Regulates paranodal junction formation . Involved in cell adhesion, cell motility and tumor metastasis (PMID:8478605, PMID:7511626). | ||
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| Other names | CD9 antigen, 5H9 antigen, Cell growth-inhibiting gene 2 protein, Leukocyte antigen MIC3, Motility-related protein, MRP-1, Tetraspanin-29, Tspan-29, p24, CD9, CD9, MIC3, TSPAN29, GIG2 | ||
| Cellular localization | Extracellular Exosome, Plasma Membrane, Membrane, Multi-Pass Membrane, Membrane | ||
| Research area | Cardiovascular | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | P21926 | ||
| Product name | Anti-CD9 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-59266 | ||
| Supplier’s Catalog No | IGX-59266 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, WB, IHC, IF, Flow cyto; Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:500, IF:1:30-1:200 | ||
| Recommended dilutions | WB: 1:500-1:5000, IHC: 1:50-1:500, IF: 1:30-1:200 | ||
| Molecular weight | |||
| Conjugate | Unconjugated | ||
| Immunogen | A synthesized peptide | ||
| Specificity | This antibody detects total endogenous levels of CD9 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
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| Clonality | Monoclonal | ||
| Isotype | Rabbit IgG | ||
| Clone ID | N/A | ||
| Concentration | Concentration can vary between different batches. | ||
| Storage buffer | Phosphate-buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | ||
| Formulation | Liquid | ||
| Purification | Affinity Purified | ||
| Handling | This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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