Anti-NFKBIA / NF kappa-B inhibitor alpha Antibody
Catalog No : IGX-59429
282.00€
201.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription. | ||
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| Other names | NF-kappa-B inhibitor alpha, I-kappa-B-alpha, IkB-alpha, IkappaBalpha, Major histocompatibility complex enhancer-binding protein MAD3, NFKBIA, IKBA, MAD3, NFKBI | ||
| Cellular localization | Cytoplasm, Nucleus | ||
| Research area | Signal Transduction | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | P25963 | ||
| Product name | Anti-NFKBIA / NF kappa-B inhibitor alpha Antibody | ||
|---|---|---|---|
| Catalog No | IGX-59429 | ||
| Supplier’s Catalog No | IGX-59429 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, WB, IHC, IP; Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, IP:1:200-1:1000 | ||
| Recommended dilutions | WB: 1:500-1:5000, IHC: 1:50-1:200, IP: 1:200-1:1000 | ||
| Molecular weight | Predicted band size: 36 KDa Observed band size: 36 KDa | ||
| Conjugate | Unconjugated | ||
| Immunogen | A synthesized peptide derived from human NFKBIA | ||
| Specificity | This antibody detects total endogenous levels of NFKBIA protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
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| Clonality | Monoclonal | ||
| Isotype | Rabbit IgG | ||
| Clone ID | N/A | ||
| Concentration | Concentration can vary between different batches. | ||
| Storage buffer | Phosphate-buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | ||
| Formulation | Liquid | ||
| Purification | Affinity Purified | ||
| Handling | This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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