EnzyAssay™ Human TGF-β1 ELISA Kit
Catalog No : IGX-14859EH
384.00€
292.00€
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| Product name | EnzyAssay™ Human TGF-β1 ELISA Kit | ||
|---|---|---|---|
| Catalog No | IGX-14859EH | ||
| Supplier’s Catalog No | IGX-14859EH | ||
| Supplier | ImuGeX | ||
| Method | Colorimetric (450nm) | ||
| Procedure duration | 3-4 h | ||
| Application | ELISA (Sandwich) | ||
| Species reactivity | Human | ||
| Sample | Cell culture supernatants, Serum, Plasma, other biological fluids | ||
| Detection limit | 8 pg/mL | ||
| Detection range | 15.6 - 1000 pg/mL | ||
| Storage | 2-8°C & -20°C | ||
|---|---|---|---|
| Other names | TGFB1, CED, DPD1, LAP, TGFB, TGFbeta, TGF-beta 1 protein, latency-associated peptide | ||
| Reactivity life | 6 months when stored properly at recommended temperature. | ||
| Note | This product is for research purpose only, not for diagnostics or therapeutics. | ||
| Description | TGF-β is capable of producing a variety of effects and virtually all cell types respond to this factor in some way. The inappropriate presence of active TGF-β1 has been implicated in a variety of pathological conditions Because of the necessity for regulating its activity tightly, TGF-β is secreted by cells in the form of an inactive complex. This complex consists of TGF-β1 associated non-covalently with a protein designated the latency associated peptide (LAP). TGF-β1 and LAP represent components of a pro-peptide that is cleaved in a post-golgi compartment prior to secretion. LAP and TGF-β1 each consist of a disulfide-linked homodimer and the association of these two components renders TGF-β1 inactive and inaccessible to anti-TGF-β antibodies. EnzyAssay™ Human TGF-β1 ELISA Kit has high sensitivity and excellent specificity for detection of Human TGF-β1. No significant cross-reactivity or interference between Human TGF-β1 and analogues was observed. | ||
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