EnzyAssay™ Human TIMP-1 ELISA Kit

Catalog No : IGX-14861EH
384.00€
292.00€

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Product name EnzyAssay™ Human TIMP-1 ELISA Kit
Catalog No IGX-14861EH
Supplier’s Catalog No IGX-14861EH
Supplier ImuGeX
Method Colorimetric (450nm)
Procedure duration 3-4 h
Application ELISA (Sandwich)
Species reactivity Human
Sample Cell culture supernatants, Serum, Plasma, other biological fluids
Detection limit 16 pg/mL
Detection range 31.25 - 2000 pg/mL
Storage 2-8°C & -20°C
Other names TIMP1, RP1-230G1.3, CLGI, EPA, EPO, FLJ90373, HCI, TIMP, erythroid potentiating activity,fibroblast collagenase inhibitor,Metalloproteinase inhibitor 1
Reactivity life 6 months when stored properly at recommended temperature.
Note This product is for research purpose only, not for diagnostics or therapeutics.
Description TIMP metallopeptidase inhibitor 1, a member of the TIMP family. The glycoprotein is a natural inhibitor of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function.Transcription of TIMP-1 is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that TIMP-1 inactivation is polymorphic in human females. TIMP-1 is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. EnzyAssay™ Human TIMP-1 ELISA Kit has high sensitivity and excellent specificity for detection of Human TIMP-1. No significant cross-reactivity or interference between Human TIMP-1 and analogues was observed.
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