EnzyAssay™ Mouse CCL2 ELISA Kit
Catalog No : IGX-14873EM
384.00€
292.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
Product name | EnzyAssay™ Mouse CCL2 ELISA Kit | ||
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Catalog No | IGX-14873EM | ||
Supplier’s Catalog No | IGX-14873EM | ||
Supplier | ImuGeX | ||
Method | Colorimetric (450nm) | ||
Procedure duration | 3-4 h | ||
Application | ELISA (Sandwich) | ||
Species reactivity | Mouse | ||
Sample | Cell culture supernatants, Serum, Plasma, other biological fluids | ||
Detection limit | 16 pg/mL | ||
Detection range | 31.25 - 2000 pg/mL |
Storage | 2-8°C & -20°C | ||
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Other names | CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, MGC9434, SCYA2, SMC-CF, monocyte chemoattractant protein-1, monocyte chemotactic and activating factor, monocyte secretory protein JE, small inducible cytokine | ||
Reactivity life | 6 months when stored properly at recommended temperature. | ||
Note | This product is for research purpose only, not for diagnostics or therapeutics. | ||
Description | CCL2 is a small cytokine belonging to the CC chemokine family that is also known as monocyte chemotactic protein-1 (MCP-1). This chemokine is produced predominantly by macrophages and endothelial cells and is a potent chemotactic factor for monocytes as a protein precursor containing signal peptide of 23 amino acids and a mature peptide of 76 amino acids. It is a monomeric polypeptide, with a molecular weight of approximately 13kDa.CCL2 recruits monocytes, memory T cells, and dendritic cells to sites of tissue injury and infection. Expression of this proinflammatory chemokine is increased in atherosclerotic lesions, and inhibition of its expression or that of its receptor, CC chemokine receptor 2 (CCR2), reduces the extent of atheroma formation in hypercholesterolemic mice. EnzyAssay™ Mouse CCL2 ELISA Kit has high sensitivity and excellent specificity for detection of Mouse CCL2. No significant cross-reactivity or interference between Mouse CCL2 and analogues was observed. |
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