EnzyAssay™ Mouse CCL2 ELISA Kit

Catalog No : IGX-14873EM
384.00€
292.00€

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Product name EnzyAssay™ Mouse CCL2 ELISA Kit
Catalog No IGX-14873EM
Supplier’s Catalog No IGX-14873EM
Supplier ImuGeX
Method Colorimetric (450nm)
Procedure duration 3-4 h
Application ELISA (Sandwich)
Species reactivity Mouse
Sample Cell culture supernatants, Serum, Plasma, other biological fluids
Detection limit 16 pg/mL
Detection range 31.25 - 2000 pg/mL
Storage 2-8°C & -20°C
Other names CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, MGC9434, SCYA2, SMC-CF, monocyte chemoattractant protein-1, monocyte chemotactic and activating factor, monocyte secretory protein JE, small inducible cytokine
Reactivity life 6 months when stored properly at recommended temperature.
Note This product is for research purpose only, not for diagnostics or therapeutics.
Description CCL2 is a small cytokine belonging to the CC chemokine family that is also known as monocyte chemotactic protein-1 (MCP-1). This chemokine is produced predominantly by macrophages and endothelial cells and is a potent chemotactic factor for monocytes as a protein precursor containing signal peptide of 23 amino acids and a mature peptide of 76 amino acids. It is a monomeric polypeptide, with a molecular weight of approximately 13kDa.CCL2 recruits monocytes, memory T cells, and dendritic cells to sites of tissue injury and infection. Expression of this proinflammatory chemokine is increased in atherosclerotic lesions, and inhibition of its expression or that of its receptor, CC chemokine receptor 2 (CCR2), reduces the extent of atheroma formation in hypercholesterolemic mice. EnzyAssay™ Mouse CCL2 ELISA Kit has high sensitivity and excellent specificity for detection of Mouse CCL2. No significant cross-reactivity or interference between Mouse CCL2 and analogues was observed.
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