EnzyAssay™ Mouse IL-17 ELISA Kit
Catalog No : IGX-14885EM
384.00€
292.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
Product name | EnzyAssay™ Mouse IL-17 ELISA Kit | ||
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Catalog No | IGX-14885EM | ||
Supplier’s Catalog No | IGX-14885EM | ||
Supplier | ImuGeX | ||
Method | Colorimetric (450nm) | ||
Procedure duration | 3-4 h | ||
Application | ELISA (Sandwich) | ||
Species reactivity | Mouse | ||
Sample | Cell culture supernatants, Serum, Plasma, other biological fluids | ||
Detection limit | 4 pg/mL | ||
Detection range | 7.8 -500 pg/mL |
Storage | 2-8°C & -20°C | ||
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Other names | IL 17, IL17A, CTLA8, IL-17, IL-17A, IL17, cytotoxic T-lymphocyte-associated antigen 8, cytotoxic T-lymphocyte-associated protein 8, cytotoxic T-lymphocyte-associated serine esterase 8, interleukin 17 (cytotoxic T-ly | ||
Reactivity life | 6 months when stored properly at recommended temperature. | ||
Note | This product is for research purpose only, not for diagnostics or therapeutics. | ||
Description | Interleukin 17 (IL-17; also known as IL-17A) is a 30 - 35 kDa variably glycosylated homodimeric protein that belongs to a unique family of cysteine-knot related proteins. Its sequence was originally isolated from an activated rodent hybridoma and termed CTLA-8 . It is synthesized as a 155 amino acid (aa) precursor that contains a 23 aa signal sequence and a 15 kDa, 132 aa mature segment. Although there are two intrachain disulfide bonds that create a ring reminiscent of those found in cysteine-knot proteins, the actual closed knot structure does not appear to form. IL-17 has one potential N-linked glycosylation site.IL-17, a T cell-derived proinf lammatory cytokine, is produced by TCRα/β+CD4-CD8- thymocytes, as well as by activated CD4+ and CD4+CD45RO+ memory T cells. EnzyAssay™ Mouse IL-17 ELISA Kit has high sensitivity and excellent specificity for detection of Mouse IL-17. No significant cross-reactivity or interference between Mouse IL-17 and analogues was observed. |
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