Anti-AMPK beta 2 antibody
Catalog No : FT-FNab00378
294.00€
0.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene. | ||
|---|---|---|---|
| Other names | |||
| Cellular localization | |||
| Research area | Signal Transduction, Metabolism | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | O43741 | ||
| Product name | Anti-AMPK beta 2 antibody | ||
|---|---|---|---|
| Catalog No | FT-FNab00378 | ||
| Supplier’s Catalog No | FNab00378 | ||
| Supplier | Fine Test (Wuhan Fine Biotech) | ||
| Host species | Rabbit | ||
| Species reactivity | Human, Mouse, Rat | ||
| Applications | ELISA, WB, IHC | ||
| Recommended dilutions | WB: 1:500 - 1:2000, IHC: 1:50 - 1:200 | ||
| Molecular weight | 35 kDa | ||
| Conjugate | Unconjugated | ||
| Immunogen | protein kinase, AMP-activated, beta 2 non-catalytic subunit | ||
| Specificity | N/A | ||
| Storage | Store at -20°C. Avoid repeated freeze and thaw cycles. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 | ||
| Formulation | Liquid | ||
| Purification | Immunogen affinity purified, ≥95% as determined by SDS-PAGE | ||
| Handling | This product contains NaN3 as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions. | ||
Product Details
© 2020 Imugex All Rights Reserved