Anti-ARHGEF1 antibody
Catalog No : FT-FNab00558
302.00€
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| Description | Seems to play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12(GNA12) and alpha-13(GNA13) subunits. Acts as GTPase-activating protein(GAP) for GNA12 and GNA13, and as guanine nucleotide exchange factor(GEF) for RhoA GTPase. Activated G alpha 13/GNA13 stimulates the RhoGEF activity through interaction with the RGS-like domain. This GEF activity is inhibited by binding to activated GNA12. Mediates angiotensin-2-induced RhoA activation. | ||
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| Other names | |||
| Cellular localization | |||
| Research area | Signal Transduction, Metabolism | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q92888 | ||
| Product name | Anti-ARHGEF1 antibody | ||
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| Catalog No | FT-FNab00558 | ||
| Supplier’s Catalog No | FNab00558 | ||
| Supplier | Fine Test (Wuhan Fine Biotech) | ||
| Host species | Rabbit | ||
| Species reactivity | Human, Mouse | ||
| Applications | ELISA, IHC, WB, IP | ||
| Recommended dilutions | WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200 | ||
| Molecular weight | 102-110 kDa | ||
| Conjugate | Unconjugated | ||
| Immunogen | Rho guanine nucleotide exchange factor(GEF) 1 | ||
| Specificity | N/A | ||
| Storage | Store at -20°C. Avoid repeated freeze and thaw cycles. | ||
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| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 | ||
| Formulation | Liquid | ||
| Purification | Immunogen affinity purified, ≥95% as determined by SDS-PAGE | ||
| Handling | This product contains NaN3 as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions. | ||
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