Anti-C4BPB antibody

Catalog No : FT-FNab01114
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Description This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants.
Other names
Cellular localization
Research area Immunology
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID P20851
Product name Anti-C4BPB antibody
Catalog No FT-FNab01114
Supplier’s Catalog No FNab01114
Supplier Fine Test (Wuhan Fine Biotech)
Host species Rabbit
Species reactivity Human, Mouse, Rat
Applications ELISA, IHC, WB, IF
Recommended dilutions WB: 1:500 - 1:2000, IHC: 1:50 - 1:100, IF: 1:50 - 1:100
Molecular weight 40-45 kDa
Conjugate Unconjugated
Immunogen complement component 4 binding protein, beta
Specificity N/A
Storage Store at -20°C. Avoid repeated freeze and thaw cycles.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration 1 mg/mL
Storage buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3
Formulation Liquid
Purification Immunogen affinity purified, ≥95% as determined by SDS-PAGE
Handling This product contains NaN3 as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions.