Imugex

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Categories: Antibodies / Primary Antibodies

Description			The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported.
Other names
Cellular localization
Research area			Metabolism, Immunology, Signal Transduction, Cell Division and Proliferation
Note			This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID			P11802

Storage			Store at -20°C. Avoid repeated freeze and thaw cycles.
Clonality			Polyclonal
Isotype			IgG
Clone ID			N/A
Concentration			1 mg/mL
Storage buffer			PBS with 0.02% sodium azide and 50% glycerol pH 7.3
Formulation			Liquid
Purification			Immunogen affinity purified, ≥95% as determined by SDS-PAGE
Handling			This product contains NaN3 as preservative, please take appropriate care when handling this product.
Reactivity life			12 months when stored properly according to instructions.