Anti-ERK1/2 antibody
Catalog No : FT-FNab02845
294.00€
0.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. | ||
|---|---|---|---|
| Other names | |||
| Cellular localization | |||
| Research area | Signal Transduction, Metabolism, Cardiovascular, Immunology, Neuroscience, Cell Division and Proliferation | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | P28482 | ||
| Product name | Anti-ERK1/2 antibody | ||
|---|---|---|---|
| Catalog No | FT-FNab02845 | ||
| Supplier’s Catalog No | FNab02845 | ||
| Supplier | Fine Test (Wuhan Fine Biotech) | ||
| Host species | Rabbit | ||
| Species reactivity | Human, Mouse, Rat | ||
| Applications | ELISA, WB, IHC | ||
| Recommended dilutions | WB: 1:500 - 1:2000, IHC: 1:50 - 1:100 | ||
| Molecular weight | 40 kDa | ||
| Conjugate | Unconjugated | ||
| Immunogen | mitogen-activated protein kinase 1 | ||
| Specificity | N/A | ||
| Storage | Store at -20°C. Avoid repeated freeze and thaw cycles. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 | ||
| Formulation | Liquid | ||
| Purification | Immunogen affinity purified, ≥95% as determined by SDS-PAGE | ||
| Handling | This product contains NaN3 as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions. | ||
Product Details
© 2020 Imugex All Rights Reserved