Anti-FADD antibody
Catalog No : FT-FNab02941
294.00€
0.00€
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| Description | Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas(CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex(DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. | ||
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| Other names | |||
| Cellular localization | |||
| Research area | Immunology, Signal Transduction | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q13158 | ||
| Product name | Anti-FADD antibody | ||
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| Catalog No | FT-FNab02941 | ||
| Supplier’s Catalog No | FNab02941 | ||
| Supplier | Fine Test (Wuhan Fine Biotech) | ||
| Host species | Rabbit | ||
| Species reactivity | Human, Mouse, Rat | ||
| Applications | ELISA, IHC, WB, IP | ||
| Recommended dilutions | WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IP: 1:50 - 1:200 | ||
| Molecular weight | 26 kDa | ||
| Conjugate | Unconjugated | ||
| Immunogen | Fas(TNFRSF6)-associated via death domain | ||
| Specificity | N/A | ||
| Storage | Store at -20°C. Avoid repeated freeze and thaw cycles. | ||
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| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 | ||
| Formulation | Liquid | ||
| Purification | Immunogen affinity purified, ≥95% as determined by SDS-PAGE | ||
| Handling | This product contains NaN3 as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions. | ||
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