Anti-FXN antibody

Catalog No : FT-FNab03255
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Description FXN, also named as FRDA, X25, m81-FXN, d-FXN, m78-FXN and i-FXN, belongs to the frataxin family. It promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. FXN may play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+; the oligomeric form but not the monomeric form has in vitro ferroxidase activity. FXN is cleaved to be 4 chains. The mature form of FXN is 14 or 18kDa.
Other names
Cellular localization
Research area Cancer, Neuroscience, Metabolism, Signal Transduction
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID Q16595
Product name Anti-FXN antibody
Catalog No FT-FNab03255
Supplier’s Catalog No FNab03255
Supplier Fine Test (Wuhan Fine Biotech)
Host species Rabbit
Species reactivity Human
Applications ELISA, WB
Recommended dilutions WB: 1:500-1:2000
Molecular weight 14 kDa
Conjugate Unconjugated
Immunogen frataxin
Specificity N/A
Storage Store at -20°C. Avoid repeated freeze and thaw cycles.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration 1 mg/mL
Storage buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3
Formulation Liquid
Purification Immunogen affinity purified, ≥95% as determined by SDS-PAGE
Handling This product contains NaN3 as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions.