Imugex

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Categories: Antibodies / Primary Antibodies

Description			The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
Other names
Cellular localization
Research area			Neuroscience, Immunology, Cardiovascular, Signal Transduction
Note			This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID			P01584

Storage			Store at -20°C. Avoid repeated freeze and thaw cycles.
Clonality			Polyclonal
Isotype			IgG
Clone ID			N/A
Concentration			1 mg/mL
Storage buffer			PBS with 0.02% sodium azide and 50% glycerol pH 7.3
Formulation			Liquid
Purification			Immunogen affinity purified, ≥95% as determined by SDS-PAGE
Handling			This product contains NaN3 as preservative, please take appropriate care when handling this product.
Reactivity life			12 months when stored properly according to instructions.