Anti-MYL2 antibody
Catalog No : FT-FNab05486
307.00€
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| Description | Contractile protein that plays a role in heart development and function(By similarity). Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion; as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin binding sites to sustain thin filament activation as a means to fine-tune myofilament calcium sensitivity to force(By similarity). During cardiogenesis plays an early role in cardiac contractility by promoting cardiac myofibril assembly(By similarity). | ||
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| Cellular localization | |||
| Research area | Neuroscience, Immunology, Cardiovascular | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | P10916 | ||
| Product name | Anti-MYL2 antibody | ||
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| Catalog No | FT-FNab05486 | ||
| Supplier’s Catalog No | FNab05486 | ||
| Supplier | Fine Test (Wuhan Fine Biotech) | ||
| Host species | Rabbit | ||
| Species reactivity | Human, Mouse, Rat | ||
| Applications | ELISA, IHC, WB | ||
| Recommended dilutions | WB: 1:500-1:2000, IHC: 1:20-1:200 | ||
| Molecular weight | 18-20 kDa | ||
| Conjugate | Unconjugated | ||
| Immunogen | myosin, light chain 2, regulatory, cardiac, slow | ||
| Specificity | N/A | ||
| Storage | Store at -20°C. Avoid repeated freeze and thaw cycles. | ||
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| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 | ||
| Formulation | Liquid | ||
| Purification | Immunogen affinity purified, ≥95% as determined by SDS-PAGE | ||
| Handling | This product contains NaN3 as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions. | ||
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