Anti-PIAS4 antibody
Catalog No : FT-FNab06431
294.00€
0.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Functions as an E3-type small ubiquitin-like modifier(SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53/TP53 pathway, the Wnt pathway and the steroid hormone signaling pathway. Involved in gene silencing. Mediates sumoylation of CEBPA, PARK7, HERC2, MYB, TCF4 and RNF168. In Wnt signaling, represses LEF1 and enhances TCF4 transcriptional activities through promoting their sumoylations. Enhances the sumoylation of MTA1 and may participate in its paralog-selective sumoylation. | ||
|---|---|---|---|
| Other names | |||
| Cellular localization | |||
| Research area | Metabolism | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q8N2W9 | ||
| Product name | Anti-PIAS4 antibody | ||
|---|---|---|---|
| Catalog No | FT-FNab06431 | ||
| Supplier’s Catalog No | FNab06431 | ||
| Supplier | Fine Test (Wuhan Fine Biotech) | ||
| Host species | Rabbit | ||
| Species reactivity | Human, Mouse, Rat | ||
| Applications | ELISA, WB | ||
| Recommended dilutions | WB: 1:500-1:2000 | ||
| Molecular weight | 60 kDa | ||
| Conjugate | Unconjugated | ||
| Immunogen | protein inhibitor of activated STAT, 4 | ||
| Specificity | N/A | ||
| Storage | Store at -20°C. Avoid repeated freeze and thaw cycles. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 | ||
| Formulation | Liquid | ||
| Purification | Immunogen affinity purified, ≥95% as determined by SDS-PAGE | ||
| Handling | This product contains NaN3 as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions. | ||
Product Details
© 2020 Imugex All Rights Reserved