Anti-Caspase 1 antibody
Catalog No : FT-FNab10015
302.00€
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| Description | CASP1(caspase-1) is also named as IL1BC, IL1BCE and belongs to the peptidase C14A family. It is a cysteine protease that regulates inflammatory processes through its capacity to process and activate the interleukin-1-beta(IL1B), IL18, and IL33 precursor proteins. The active caspase-1 can increase cellular membrane permeability and intracellular calcium levels, which facilitates lysosome exocytosis and release of host antimicrobial factors and microbial products(PMID:21804020). It has 5 isoforms produced by alternative splicing. | ||
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| Other names | |||
| Cellular localization | |||
| Research area | Signal Transduction, Metabolism, Cardiovascular, Neuroscience | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | P29466 | ||
| Product name | Anti-Caspase 1 antibody | ||
|---|---|---|---|
| Catalog No | FT-FNab10015 | ||
| Supplier’s Catalog No | FNab10015 | ||
| Supplier | Fine Test (Wuhan Fine Biotech) | ||
| Host species | Rabbit | ||
| Species reactivity | Human, Mouse | ||
| Applications | ELISA, WB, IHC | ||
| Recommended dilutions | WB: 1:200-1:2000, IHC: 1:50-1:500 | ||
| Molecular weight | 45-47 kDa, 30 kDa, 35 kDa | ||
| Conjugate | Unconjugated | ||
| Immunogen | caspase 1 | ||
| Specificity | N/A | ||
| Storage | Store at -20°C. Avoid repeated freeze and thaw cycles. | ||
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| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 | ||
| Formulation | Liquid | ||
| Purification | Immunogen affinity purified, ≥95% as determined by SDS-PAGE | ||
| Handling | This product contains NaN3 as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions. | ||
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