Anti-Caspase 8 antibody
Catalog No : FT-FNab10024
302.00€
0.00€
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| Description | Caspase 8, also named as MCH5, MACH, FLICE, and CAP4, belongs to the peptidase C14A family. It may participate in the GZMB apoptotic pathways and functions as an upstream regulator in a-bisabolol-induced apoptosis. Caspase 8 catalyzes an essential intermediate step in the ubiquitination and proteasome-mediated degradation of IRF3(PMID:21816816). It may control diabetic embryopathy-associated apoptosis via Caspase 8 is expressed as nine isoforms by alternative splicing with the molecular mass from 26 kDa to 62 kDa. This antibodycan recognize pro-and cleaved-caspase 8. | ||
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| Research area | Signal Transduction, Metabolism, cancer | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q14790 | ||
| Product name | Anti-Caspase 8 antibody | ||
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| Catalog No | FT-FNab10024 | ||
| Supplier’s Catalog No | FNab10024 | ||
| Supplier | Fine Test (Wuhan Fine Biotech) | ||
| Host species | Rabbit | ||
| Species reactivity | Human, Mouse | ||
| Applications | ELISA, WB, IHC | ||
| Recommended dilutions | WB: 1:500-1:2000, IHC: 1:50-1:500 | ||
| Molecular weight | 53-57 kDa, 32-45 kDa | ||
| Conjugate | Unconjugated | ||
| Immunogen | caspase 8, apoptosis-related cysteine peptidase | ||
| Specificity | N/A | ||
| Storage | Store at -20°C. Avoid repeated freeze and thaw cycles. | ||
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| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 | ||
| Formulation | Liquid | ||
| Purification | Immunogen affinity purified, ≥95% as determined by SDS-PAGE | ||
| Handling | This product contains NaN3 as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions. | ||
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