Anti-PP1A antibody

Catalog No : FT-FNab10319
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Description The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Other names
Cellular localization
Research area Epigenetics, Neuroscience, Metabolism, Signal Transduction
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID P62136
Product name Anti-PP1A antibody
Catalog No FT-FNab10319
Supplier’s Catalog No FNab10319
Supplier Fine Test (Wuhan Fine Biotech)
Host species Rabbit
Species reactivity Human, Mouse
Applications ELISA, WB, IHC
Recommended dilutions WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Molecular weight 38-50kDa
Conjugate Unconjugated
Immunogen protein phosphatase 1, catalytic subunit, alpha isoform
Specificity N/A
Storage Store at -20°C. Avoid repeated freeze and thaw cycles.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration 1 mg/mL
Storage buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3
Formulation Liquid
Purification Immunogen affinity purified, ≥95% as determined by SDS-PAGE
Handling This product contains NaN3 as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions.