Anti-HDAC3 antibody

Catalog No : FT-FNab10321
294.00€
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Description Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
Other names
Cellular localization
Research area Epigenetics, Cardiovascular, Metabolism
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID O15379
Product name Anti-HDAC3 antibody
Catalog No FT-FNab10321
Supplier’s Catalog No FNab10321
Supplier Fine Test (Wuhan Fine Biotech)
Host species Rabbit
Species reactivity Human
Applications ELISA, IHC, WB
Recommended dilutions WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Molecular weight 49 kDa
Conjugate Unconjugated
Immunogen histone deacetylase 3
Specificity N/A
Storage Store at -20°C. Avoid repeated freeze and thaw cycles.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration 1 mg/mL
Storage buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3
Formulation Liquid
Purification Immunogen affinity purified, ≥95% as determined by SDS-PAGE
Handling This product contains NaN3 as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions.