Anti-c-MYC antibody

Catalog No : FT-FNab10342
294.00€
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Description MYC contains one basic helix-loop-helix(bHLH) domain. This protein is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. It seems to activate the transcription of growth-related genes. It binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. This antibody is a rabbit polyclonal antibody raised against recombinant protein of human MYC.The 50kDa band recognized by antibody is the native form of MYC, while the other bands, between 60-70kDa, are the phosphorylated form of MYC [PMID: 12189186]
Other names
Cellular localization
Research area Epigenetics, Metabolism, Immunology, Cancer, Neuroscience, Stem Cells, Cell Division and Proliferation
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID P01106
Product name Anti-c-MYC antibody
Catalog No FT-FNab10342
Supplier’s Catalog No FNab10342
Supplier Fine Test (Wuhan Fine Biotech)
Host species Rabbit
Species reactivity Human, Mouse, Rat
Applications ELISA, WB
Recommended dilutions WB: 1:500-1:2000
Molecular weight 50-60 kDa
Conjugate Unconjugated
Immunogen v-myc myelocytomatosis viral oncogene homolog(avian)
Specificity N/A
Storage Store at -20°C. Avoid repeated freeze and thaw cycles.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration 1 mg/mL
Storage buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3
Formulation Liquid
Purification Immunogen affinity purified, ≥95% as determined by SDS-PAGE
Handling This product contains NaN3 as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions.