Anti-SIRT1 antibody

Catalog No : FT-FNab10371
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Description This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.
Other names
Cellular localization
Research area Neuroscience, Stem Cells, Metabolism, Developmental biology
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID Q96EB6
Product name Anti-SIRT1 antibody
Catalog No FT-FNab10371
Supplier’s Catalog No FNab10371
Supplier Fine Test (Wuhan Fine Biotech)
Host species Rabbit
Species reactivity Human
Applications ELISA, WB, IHC
Recommended dilutions WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Molecular weight 130 kDa
Conjugate Unconjugated
Immunogen sirtuin (silent mating type information regulation 2 homolog) 1
Specificity N/A
Storage Store at -20°C. Avoid repeated freeze and thaw cycles.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration 1 mg/mL
Storage buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3
Formulation Liquid
Purification Immunogen affinity purified, ≥95% as determined by SDS-PAGE
Handling This product contains NaN3 as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions.