Anti-CaV1.1 Antibody
Catalog No : IGX-2107
277.00€
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| Description | Pore-forming, alpha-1S subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Calcium channels containing the alpha-1S subunit play an important role in excitation-contraction coupling in skeletal muscle via their interaction with RYR1, which triggers Ca2+ release from the sarcplasmic reticulum and ultimately results in muscle contraction. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. | ||
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| Other names | CCACNA1S, CAC1S, CACH1; Cach1b; CACN1; CACNA1S; CACNL1A3; Calcium channel; Calcium channel L type, alpha-1 polypeptide, isoform 3 skeletal muscle, Voltage-gated calcium channel subunit alpha Cav1.1 | ||
| Cellular localization | Plasma membrane, T-tubule | ||
| Research area | Cardiovascular, Neuroscience, Signal Transduction | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q13698 | ||
| Product name | Anti-CaV1.1 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-2107 | ||
| Supplier’s Catalog No | IGX-2107 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Huma, Predicted reactivity: Bovine, Rabbit, Pig, Canine (reactivity is predicted based on sequence homology). | ||
| Applications | WB, ELISA | ||
| Recommended dilutions | WB: 1:500-1:2000, ELISA: 1:20000-1:40000 | ||
| Molecular weight | Predicted band size: 212 KDa. Observed band size: 212 KDa | ||
| Conjugate | Unconjugated | ||
| Immunogen | A synthetic peptide derived from human CCACNA1S (CaV1.1) corresponding to N-terminal amino acids. | ||
| Specificity | CaV1.1 antibody detects endogenous levels of total CaV1.1 protein. | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
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| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4), 150mM NaCl, 0.02% sodium azide and 50% glycerol | ||
| Formulation | Liquid | ||
| Purification | Immunogen Affinity Purified | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions. | ||
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