Anti-CaV1.3 Antibody
Catalog No : IGX-2117
277.00€
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| Description | Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1D gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, and by benzothiazepines | ||
|---|---|---|---|
| Other names | CACNA1D,l CACH3, CACN4, CACNL1A2, CCHL1A2, Calcium channel, L type, alpha-1 polypeptide, isoform 2, Voltage-gated calcium channel subunit alpha Cav1.3, Voltage-dependent L-type calcium channel subunit alpha-1D | ||
| Cellular localization | Membrane | ||
| Research area | Cardiovascular, Neuroscience, Signal Transduction | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q01668 | ||
| Product name | Anti-CaV1.3 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-2117 | ||
| Supplier’s Catalog No | IGX-2117 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human, Mouse, Rat; Predicted: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken | ||
| Applications | WB, ELISA | ||
| Recommended dilutions | WB: 1:1000-3000, ELISA: 1:20000-1:40000 | ||
| Molecular weight | Predicted band size: 245 KDa. Observed band size: 245 KDa | ||
| Conjugate | Unconjugated | ||
| Immunogen | A synthetic peptide derived from human CACNA1D corresponding to amino acids in the internal region. | ||
| Specificity | CaV1.3 Antibody detects endogenous levels of total CaV1.3 protein. | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4), 150mM NaCl, 0.02% sodium azide and 50% glycerol | ||
| Formulation | Liquid | ||
| Purification | Immunogen Affinity Purified | ||
| Handling | This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions. | ||
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