Anti-CaV1.3 Antibody

Catalog No : IGX-2117
277.00€
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Description Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1D gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, and by benzothiazepines
Other names CACNA1D,l CACH3, CACN4, CACNL1A2, CCHL1A2, Calcium channel, L type, alpha-1 polypeptide, isoform 2, Voltage-gated calcium channel subunit alpha Cav1.3, Voltage-dependent L-type calcium channel subunit alpha-1D
Cellular localization Membrane
Research area Cardiovascular, Neuroscience, Signal Transduction
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID Q01668
Product name Anti-CaV1.3 Antibody
Catalog No IGX-2117
Supplier’s Catalog No IGX-2117
Supplier ImuGeX
Host species Rabbit
Species reactivity Human, Mouse, Rat; Predicted: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken
Applications WB, ELISA
Recommended dilutions WB: 1:1000-3000, ELISA: 1:20000-1:40000
Molecular weight Predicted band size: 245 KDa. Observed band size: 245 KDa
Conjugate Unconjugated
Immunogen A synthetic peptide derived from human CACNA1D corresponding to amino acids in the internal region.
Specificity CaV1.3 Antibody detects endogenous levels of total CaV1.3 protein.
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration 1 mg/mL
Storage buffer Phosphate-buffered saline (pH 7.4), 150mM NaCl, 0.02% sodium azide and 50% glycerol
Formulation Liquid
Purification Immunogen Affinity Purified
Handling This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions.