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Categories: Biochemicals / Biochemicals

Product name			Asialo-Ganglioside GM1 (Ceramide tetrahexoside, Gangliotetraosylceramide, Asialoganglioside-GM1, GA1-Ganglioside)
Catalog No			USB-207067
Supplier’s Catalog No			207067
Supplier			US Biologicals
Source antigen			Semisynthetic
Reactivity
Cross reactivity
Applications
Molecular weight			1255.6

Storage			-20°C
Other names
Grade			Highly Purified
Purity			≥98% (TLC)
Form			Supplied as a lyophilized powder.
Reactivity life			12 months
Note			For reserch purpose only
Description			Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis and metastasis. The accumulation of gangliosides has been linked to several diseases. Removing the sialic acid from monosialoganglioside GM1 inhibits its ability to bind cholera toxin. Asialo-ganglioside GM1 does not block the binding of cholera toxin to cellular GM1. CAS Number: 71012-19-6 Source: Semisynthetic Sequence: GgOse4Cer; beta-Gal-(1-3)-beta-GalNAc-(1-4)-beta-Gal-(1-4)-beta-Glc-(1-1)-Cer Solubility: Chloroform:methanol (2:1) Molecular Weight: ~1255.6 (calculated on sphingosine C18:1 and stearic acid) Purity: ≥98% (TLC) Identity: Determined by 1H-NMR, MS and HPTLC. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile buffer. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.