Treponema pallidum p17, Recombinant (Syphilis)
Catalog No : USB-T8300-18C
1109.23€
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| Product name | Treponema pallidum p17, Recombinant (Syphilis) | ||
|---|---|---|---|
| Catalog No | USB-T8300-18C | ||
| Supplier’s Catalog No | T8300-18C | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, E. coli | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | |||
| Storage | -20°C | ||
|---|---|---|---|
| Other names | |||
| Grade | Highly Purified | ||
| Purity | ≥ 95% (SDS-PAGE and HPLC); Inclusion bodies. | ||
| Form | Supplied as a liquid in 8M urea, 10mM Tris-HCl, pH 8.0, 1mM EDTA, 1mM DTT. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | ≥ 95% (SDS-PAGE and HPLC); Inclusion bodies. | ||
| Description | Treponema pallidum is the causative agent of syphilis. It is a spirochete, a helical to sinusoidal bacterium with outer and cytoplasmic membranes, a thin peptidoglycan layer, and periplasmic flagella. Mechanisms of T. pallidum pathogenesis are poorly understood. No known virulence factors have been identified, and the outer membrane is mostly lipid with a paucity of proteins. Consequently, existing diagnostic tests for syphilus are suboptimal, and no vaccine against T. pallidum is available. TIGR sequenced the genome of T. pallidum subsp. pallidum (strain Nichols) by the whole genome random sequencing method. The T. pallidum genome is a circular chromosome of 1,138,006 base pairs containing a total of 1041 predicted open reading frames. Treponema pallidum p17 recombinant protein containing Beta-galactosidase (114 kDa) fusion partner. Molecular weight is 120 kDa. Immunoreactive with human T. pallidum positive serum. Applications: Suitable for use in ELISA, Western Blot and Immunochromatographic assays. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
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