Hepatitis C Virus, Core, NS3, NS4, NS5, Recombinant (HCV)
Catalog No : USB-H1920-17Q2
560.94€
0.00€
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| Product name | Hepatitis C Virus, Core, NS3, NS4, NS5, Recombinant (HCV) | ||
|---|---|---|---|
| Catalog No | USB-H1920-17Q2 | ||
| Supplier’s Catalog No | H1920-17Q2 | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, E. coli | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | |||
| Storage | -20°C | ||
|---|---|---|---|
| Other names | |||
| Grade | Purified | ||
| Purity | ~90% by SDS-PAGE | ||
| Form | Supplied as a liquid in 50mM Tris, pH 8.50 | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | ~90% by SDS-PAGE | ||
| Description | The hepatitis C virus (HCV) core protein represents the first 191aa of the viral precursor polyprotein and is cotranslationally inserted into the membrane of the endoplasmic reticulum (ER Hepatitis C virus (HCV) core is a viral structural protein; it also participates in some cellular processes, including transcriptional regulation. However, the mechanisms of core-mediated transcriptional regulation remain poorly understood. Hepatitis C virus (HCV) core protein is thought to contribute to HCV pathogenesis through its interaction with various signal transduction pathways In addition, HCV core antigen is a recently developed marker of hepatitis C infection. It is remarkably efficient at establishing persistent infection, suggesting that it has evolved one or more strategies aimed at evading the host immune response. T cell responses, including interferon-gamma production, are severely suppressed in chronic HCV patients. The HCV core protein has been previously shown to circulate in the bloodstream of HCV-infected patients and inhibit host immunity through an interaction with gC1qR. Source: Recombinant corresponding to Hepatitis C virus, core-NS3-NS4-NS5 chimera, expressed in E.coli. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
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