Influenza A, H3N2, Wyoming 3/03, Hemagglutinin, Recombinant, aa18-347
Catalog No : USB-209029
417.25€
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Product name | Influenza A, H3N2, Wyoming 3/03, Hemagglutinin, Recombinant, aa18-347 | ||
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Catalog No | USB-209029 | ||
Supplier’s Catalog No | 209029 | ||
Supplier | US Biologicals | ||
Source antigen | Recombinant, 293 cells | ||
Reactivity | |||
Cross reactivity | |||
Applications | |||
Molecular weight | 75 |
Storage | -20°C | ||
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Other names | |||
Grade | Highly Purified | ||
Purity | ~95% (SDS-PAGE) | ||
Form | Supplied as a liquid in 10mM sodium phosphate, pH 7.4, 150mM sodium chloride, 0.1% BSA, 0.05% azide, 25% glycerol. | ||
Reactivity life | 12 months | ||
Note | For reserch purpose only | ||
Purity | ~95% (SDS-PAGE) | ||
Description | Influenza A (H1N1) virus is a subtype of influenza A virus and was the most common cause of human influenza (flu) in 2009. Some strains of H1N1 are endemic in humans and cause a small fraction of all influenza-like illness and a small fraction of all seasonal influenza. H1N1 strains caused a few percent of all human flu infections in 2004-2005. Other strains of H1N1 are endemic in pigs (swine influenza) and in birds (avian influenza). In June 2009, the World Health Organization declared the new strain of swine- origin H1N1 as a pandemic. This strain is often called swine flu by the public media. Swine influenza (also called swine flu, or pig flu) is an infection by any one of several types of swine influenza virus. Swine influenza virus (SIV) is any strain of the influenza family of viruses that is endemic in pigs. As of 2009, the known SIV strains include influenza C and the subtypes of influenza A known as H1N1, H1N2, H3N1, H3N2, and H2N3. The Influenza A Virus is a globular particle about 100nm in diameter, sheathed in a lipid bilayer derived from the plasma membrane of its host. Studded in the lipid bilayer are two integral membrane proteins some 500 molecules of hemagglutinin ("H") and some 100 molecules of neuraminidase ("N"). Within the lipid bilayer are 3000 molecules of matrix protein and 8 pieces of RNA. Each of the 8 RNA molecules is associated with many copies of a nucleoprotein, several molecules of the three subunits of its RNA polymerase some "non-structural" protein molecules of uncertain function. H3N2 is a subtype of the influenza A virus. Its name derives from the forms of the two kinds of proteins on the surface of its coat, hemagglutinin (H) and neuraminidase (N). H3N2 exchanges genes for internal proteins with other influenza subtypes. H3N2 has tended to dominate in prevalence over H1N1, H1N2, and influenza B. H3N2 strain descended from H2N2by antigenic shift, in which genes from multiple subtypes re-assorted to form a new virus. Both the H2N2and H3N2 strains contained genes from avian influenza viruses. Source: Recombinant protein corresponding to full-length H3N2 A/Wyoming/2003/3, aa18-347, glycosylated with N-linked sugars, expressed in 293 cells. Molecular Weight: ~75kD Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1ug/well Western Blot: 0.1-1ug/strip Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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