Tick-borne Encephalitis virus NS1, Recombinant (TBEV)

Catalog No : USB-242957
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Product name Tick-borne Encephalitis virus NS1, Recombinant (TBEV)
Catalog No USB-242957
Supplier’s Catalog No 242957
Supplier US Biologicals
Source antigen Recombinant
Reactivity
Cross reactivity
Applications
Molecular weight
Storage -70°C
Other names
Grade Highly Purified
Purity ≥90% pure by SDS-PAGE
Form Supplied as a liquid in sterile dH2O, 0.09% sodium azide.
Reactivity life 3 months
Note For reserch purpose only
Purity ≥90% pure by SDS-PAGE
Description Tick-Borne Encephalitis Virus NS1 protein is produced entirely from human cell lines. The Tick-Borne Encephalitis Virus NS1 protein has been manufactured in response to a need for a highly purified, concentrated protein for use in serological based diagnostic products. The antigen is in its native folding state, and possesses all post-translational modifications. This advanced approach results in a product which delivers optimal antigenicity due to its human origin. The Tick-borne encephalitis virus (TBEV) is a Flavivirus which is transmitted to humans through a bite from an infected tick. Tick-borne encephalitis (TBE) is endemic in Europe and Asia with an average of 8,500 cases per year in Europe (wwwnc.cdc.gov/travel/yellowbook/2014/). TBE infected patients typically present with influenza-like symptoms and the disease is neuroinvasive often manifesting as meningitis, encephalitis or meningoencephalitis. Long-lasting or permanent neuropsychiatric sequelae are reported in 10 to 20% of patients. Tick-Borne Encephalitis Virus NS1 is presented in a hexameric state. Source: Encephalitis Virus NS1, Tick-Borne, strain Neudoerfl, from washed and lysed purified protozoa. Inactivation: Cells are lysed by sonication and freeze/thawing. Confirmed inactive by no visible growth in permissive media after 5 days compared to positive control. Storage and Stability: All NS1 products are shipped at ambient temperature. Extensive stability tests have shown no negative effects on antigen performance for 7 days of shipping including several freeze/thaw cycles. Aliquot to avoid repeated freezing and thawing and store at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: No test guarantees a product to be non-infectious. All materials should be handled as if potentially infectious. Generally accepted laboratory practices appropriate for infectious materials should be employed when handling this product.