Rickettsia 17kD Surface Antigen Family, Recombinant, aa46-122, His-Tag

Catalog No : USB-367008
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Product name Rickettsia 17kD Surface Antigen Family, Recombinant, aa46-122, His-Tag
Catalog No USB-367008
Supplier’s Catalog No 367008
Supplier US Biologicals
Source antigen
Reactivity
Cross reactivity
Applications
Molecular weight
Storage -70°C
Other names
Grade Purified
Purity ~90% (SDS-PAGE under reducing conditions)
Form Supplied as a liquid in 10mM Tris-HCl, pH 7.5, 0.5M sodium chloride, 1M Imidazole, 8M Urea.
Reactivity life 6 months
Note For reserch purpose only
Purity ~90% (SDS-PAGE under reducing conditions)
Description Recombinant protein corresponding to Rickettsia 17kD Surface Antigen Family (amino acids 46-122, UniProt accession #B8LAD2), fused to a 6x His-Tag. Rickettsia rickettsii is an obligate intracellular Gram-negative bacterium that causes Rocky Mountain spotted fever (RMSF), a serious life-threatening disease. RMSF was first found in the Snake River Valley of Idaho in 1896 and described by Edward E Maxey [1]. Patients suffering from RMSF usually present fever, headache, myalgias, and rash, as well as a history of tick bite or contact. For serious R. rickettsii infection, patients will develop symptoms of acute lung edema, renal failure, and/or encephalitis [2], [3] due to wide spread vasculitis caused by rickettsial infection of endothelial cells lining the small blood vessels in these vital organs [4], [5]. Appearance: Supplied as a liquid. Purity: ~90% (SDS-PAGE under reducing conditions) Applications: Suitable for use in ELISA, Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Aliquot and store at -20°C or lower. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.