Rickettsia 17kD Surface Antigen Family, Recombinant, aa46-122, His-Tag
Catalog No : USB-367008
1288.54€
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Product name | Rickettsia 17kD Surface Antigen Family, Recombinant, aa46-122, His-Tag | ||
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Catalog No | USB-367008 | ||
Supplier’s Catalog No | 367008 | ||
Supplier | US Biologicals | ||
Source antigen | |||
Reactivity | |||
Cross reactivity | |||
Applications | |||
Molecular weight |
Storage | -70°C | ||
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Other names | |||
Grade | Purified | ||
Purity | ~90% (SDS-PAGE under reducing conditions) | ||
Form | Supplied as a liquid in 10mM Tris-HCl, pH 7.5, 0.5M sodium chloride, 1M Imidazole, 8M Urea. | ||
Reactivity life | 6 months | ||
Note | For reserch purpose only | ||
Purity | ~90% (SDS-PAGE under reducing conditions) | ||
Description | Recombinant protein corresponding to Rickettsia 17kD Surface Antigen Family (amino acids 46-122, UniProt accession #B8LAD2), fused to a 6x His-Tag. Rickettsia rickettsii is an obligate intracellular Gram-negative bacterium that causes Rocky Mountain spotted fever (RMSF), a serious life-threatening disease. RMSF was first found in the Snake River Valley of Idaho in 1896 and described by Edward E Maxey [1]. Patients suffering from RMSF usually present fever, headache, myalgias, and rash, as well as a history of tick bite or contact. For serious R. rickettsii infection, patients will develop symptoms of acute lung edema, renal failure, and/or encephalitis [2], [3] due to wide spread vasculitis caused by rickettsial infection of endothelial cells lining the small blood vessels in these vital organs [4], [5]. Appearance: Supplied as a liquid. Purity: ~90% (SDS-PAGE under reducing conditions) Applications: Suitable for use in ELISA, Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Aliquot and store at -20°C or lower. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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