Rickettsia japonica 17kD Surface Antigen (omp), Strain ATCC VR-1363/YH, Recombinant, aa20-159, His-Tag/Myc-Tag

Catalog No : USB-367195
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Product name Rickettsia japonica 17kD Surface Antigen (omp), Strain ATCC VR-1363/YH, Recombinant, aa20-159, His-Tag/Myc-Tag
Catalog No USB-367195
Supplier’s Catalog No 367195
Supplier US Biologicals
Source antigen Recombinant, Mammalian cell
Reactivity
Cross reactivity
Applications
Molecular weight
Storage -20°C
Other names
Grade Purified
Purity ~90% (SDS-PAGE)
Form Supplied as a liquid in Tris, 50% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity ~90% (SDS-PAGE)
Description Recombinant protein corresponding to full length Rickettsia japonica 17kD Surface Antigen (omp) (strain ATCC VR-1363/YH) (aa20-159, UniProt accession #Q52764), fused to His-Tag at N-terminal and Myc-tag at C-terminal, expressed in mammalian cell. Rickettsia rickettsii is an obligate intracellular Gram-negative bacterium that causes Rocky Mountain spotted fever (RMSF), a serious life-threatening disease. RMSF was first found in the Snake River Valley of Idaho in 1896 and described by Edward E Maxey [1]. Patients suffering from RMSF usually present fever, headache, myalgias, and rash, as well as a history of tick bite or contact. For serious R. rickettsii infection, patients will develop symptoms of acute lung edema, renal failure, and/or encephalitis [2], [3] due to wide spread vasculitis caused by rickettsial infection of endothelial cells lining the small blood vessels in these vital organs [4], [5]. Appearance: Supplied as a liquid in Tris, 50% glycerol. Purity: ~90% (SDS-PAGE) AA Sequence: C NGPGGMNKQG TGTLLGGAGG ALLGSQFGKG TGQLVGVGVG ALLGAVLGGQ IGAGMDEQDR RLAELTSQRA LETAPSGSNV EWRNPDNGNY GYVTPNKTYR NSTGQYCREY TQTVVIGGKQ QKAYGNACRQ PDGQWQVVN Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.