HAVCR2, Recombinant, Human, aa22-202, hIgG-His-Tag (Hepatitis A Virus Cellular Receptor 2)

Catalog No : USB-369071
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Product name HAVCR2, Recombinant, Human, aa22-202, hIgG-His-Tag (Hepatitis A Virus Cellular Receptor 2)
Catalog No USB-369071
Supplier’s Catalog No 369071
Supplier US Biologicals
Source antigen Recombinant, human from insect cell line
Reactivity
Cross reactivity
Applications
Molecular weight 47.3
Storage -20°C
Other names
Grade Purified
Purity ~85% (SDS-PAGE)
Form Supplied as a liquid in PBS, pH 7.4, 10% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity ~85% (SDS-PAGE)
Description HAVCR2, also known as hepatitis A virus cellular receptor 2, is a transmembrane glycoprotein expressed on the surface of terminally differentiated Th1 cells but not on Th2 cells. It was the first surface molecule that specificallyidentifies Th1 cells in both mice and human. It interactions with Galectin-9 can alternatively trigger immune stimulatory effects, such as the coactivation of NK cell cytotoxicity. Source: Recombinant protein corresponding to aa22-202 from human HAVCR2 fussed to hlgH-His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~47.3kD (423aa) 40-57kD (SDS-PAGE under reducing conditions) AA Sequence: ADLSEVEYRA EVGQNAYLPC FYTPAAPGNL VPVCWGKGAC PVFECGNVVL RTDERDVNYW TSRYWLNGDF RKGDVSLTIE NVTLADSGIY CCRIQIPGIM NDEKFNLKLV IKPAKVTPAP TRQRDFTAAF PRMLTTRGHG PAETQTLGSL PDINLTQIST LANELRDSRL ANDLRDSGAT IRIGLEPKSC DKTHTCPPCP APELLGGPSV FLFPPKPKDT LMISRTPEVT CVVVDVSHED PEVKFNWYVD GVEVHNAKTK PREEQYNSTY RVVSVLTVLH QDWLNGKEYK CKVSNKALPA PIEKTISKAK GQPREPQVYT LPPSRDELTK NQVSLTCLVK GFYPSDIAVE WESNGQPENN YKTTPPVLDS DGSFFLYSKL TVDKSRWQQG NVFSCSVMHE ALHNHYTQKS LSLSPGKHHH HHH Endotoxin: ~1EU/1ug (LAL) Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.