Dengue Virus Serotype 4 NS1, Strain Dominica/814669 /1981, Recombinant, Mammalian, His-Tag
Catalog No : USB-397634
629.90€
0.00€
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| Product name | Dengue Virus Serotype 4 NS1, Strain Dominica/814669 /1981, Recombinant, Mammalian, His-Tag | ||
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| Catalog No | USB-397634 | ||
| Supplier’s Catalog No | 397634 | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, 293 human cells | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | |||
| Storage | -20°C | ||
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| Other names | |||
| Grade | Highly Purified | ||
| Purity | ~95% (SDS-PAGE) | ||
| Form | Supplied as a liquid in 20mM Tris-HCl, pH 8.5, 150mM sodium chloride. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | ~95% (SDS-PAGE) | ||
| Description | Dengue Virus Serotype 4 NS1 protein has been manufactured in response to the unmet need for highly purified, concentrated proteins for use in vaccine development (including use as an immunogen) and serological based diagnostic assays. Dengue Virus Serotype 4 NS1 protein is engineered on human cell lines using state-of-the-art expression techniques. The resultant hexameric presentation is believed to be the biologically active form of NS1 involved in key aspects of dengue pathogenesis. Dengue Virus Serotype 4 NS1 protein is purified to a high degree, are in their native folding state, and possess all post-translational modifications. This advanced approach results in a product which delivers optimal antigenicity due to its human origin. With more than one-third of the world’s population living in areas at risk of transmission, dengue infection is a leading cause of illness and death in the tropics and subtropics. As many as 100 million people are infected yearly. Dengue is caused by any one of four related viruses transmitted by mosquitoes. There are no vaccines available to prevent infection with dengue virus. This Dengue Virus Serotype 4 NS1 protein has been well received by a wide number of researchers. The proteins are endorsed by the Division of Infectious Disease & Vaccinology at the University of California, Berkeley. Professor Eva Harris states: “For several of our dengue research projects at the University of California, Berkeley, we had been searching for purified DENV NS1 protein from all four serotypes which could offer the advantage of being derived from a mammalian expression system. In our hands, this DENV NS1 proteins have performed extremely well in a range of applications and have helped advance our research program”. Based on the same developmental approach as used for Dengue Virus Serotype 4 NS1 protein, this also offers NS1 proteins for West Nile Virus and Yellow Fever. Used in combination, the proteins are ideal for determining the integrity of vaccines in development and well as serological based IVD’s. Source: Recombinant protein corresponding to Dominica/814669/1981 strain of Dengue Virus Serotype 4 NS1, fused to His-Tag at C-terminal, expressed in 293 human cells. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
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