Rubella K2S, HPV-77 Strain
Catalog No : USB-407374
1525.33€
0.00€
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| Product name | Rubella K2S, HPV-77 Strain | ||
|---|---|---|---|
| Catalog No | USB-407374 | ||
| Supplier’s Catalog No | 407374 | ||
| Supplier | US Biologicals | ||
| Source antigen | Vero cells | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | |||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | |||
| Grade | Purified | ||
| Purity | Vero cells infected with Rubella release virus particles into the culture supernatant. Supernatant is harvested and clarified. The material is then concentrated by crossflow ultrafiltration. The virus suspension is then purified by two cycles of sucrose density gradient centrifugation. | ||
| Form | Supplied as a liquid in NTE (sodium chloride, TRIS, EDTA). | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | Vero cells infected with Rubella release virus particles into the culture supernatant. Supernatant is harvested and clarified. The material is then concentrated by crossflow ultrafiltration. The virus suspension is then purified by two cycles of sucrose density gradient centrifugation. | ||
| Description | Rubella causes a mild rash illness of children and adults known as German measles. There is often pharyngitis and enlargement of the cervical lymph nodes. Infection often occurs during childhood with many infections being asymptomatic and complications being rare. However, infection of women in the first 16 weeks of pregnancy can lead to congenital defects developing in the foetus such as cataracts, nerve deafness and cardiac abnormalities. Antibody in women of childbearing age protects the foetus from being infected and thereby prevents congenital abnormalities from developing. Rubella virus is classified as a toga virus. It is immunologically distinct from other known viruses. The virus particle is spherical with a diameter of 60 - 70 nm and contains a single strand of RNA in a nucleocapsid surrounded by a lipid envelope. It has three structural proteins; E1 and E2, which are associated with the viral envelope and C which forms the nucleocapsid with RNA. E1 is reactive with IgM and IgG antibodies and is the antigen responsible for haemagglutination activity. E2 and C induce IgG antibodies but E1 is most important to antibody testing. Source: Rubella K2S, strain HPV-77, from Vero cells. Applications: Suitable for use in a variety of immunoassay formats including micro well ELISA, latex agglutination and IgM detection assays. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Inactivation: Rubella K2S antigen is inactivated by exposing the material to UV light. This method was chosen to maximize loss of infectivity with a minimum loss of antigenicity. Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70°C. Aliquots are stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | ||
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