Nipah Virus G, Recombinant

Catalog No : USB-474304
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Product name Nipah Virus G, Recombinant
Catalog No USB-474304
Supplier’s Catalog No 474304
Supplier US Biologicals
Source antigen Recombinant, Insect Cells
Reactivity
Cross reactivity
Applications
Molecular weight 50
Storage -20°C
Other names
Grade Purified
Purity Purified by a multi-step procedure including affinity chromatography
Form Supplied as a liquid in PBS, pH 7.4, 5% BSA. No preservative added.
Reactivity life 6 months
Note For reserch purpose only
Purity Purified by a multi-step procedure including affinity chromatography
Description Nipah virus (NiV) is a member of the family Paramyxoviridae, genus Henipavirus. NiV was initially isolated and identified in 1999 during an outbreak of encephalitis and respiratory illness among pig farmers and people with close contact with pigs in Malaysia and Singapore. Its name originated from Sungai Nipah, a village in the Malaysian Peninsula where pig farmers became ill with encephalitis. Given the relatedness of NiV to Hendra virus, bat species were quickly singled out for investigation and flying foxes of the genus Pteropus were subsequently identified as the reservoir for NiV. In the 1999 outbreak, Nipah virus caused a relatively mild disease in pigs, but nearly 300 human cases with over 100 deaths were reported. In order to stop the outbreak, more than a million pigs were euthanized, causing tremendous trade loss for Malaysia. Since this outbreak, no subsequent cases (in neither swine nor human) have been reported in either Malaysia or Singapore. In 2001, NiV was again identified as the causative agent in an outbreak of human disease occurring in Bangladesh. Genetic sequencing confirmed this virus as Nipah virus, but a strain different from the one identified in 1999. In the same year, another outbreak was identified retrospectively in Siliguri, India with reports of person-to-person transmission in hospital settings (nosocomial transmission). Unlike the Malaysian NiV outbreak, outbreaks occur almost annually in Bangladesh and have been reported several times in India. Source: Recombinant protein corresponding to Nipah Virus G, Malaysia strain, expressed in Insect Cells. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Molecular Weight: ~50kD on a 12% SDS-PAGE. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.