Chikungunya Virus E2 Envelope Protein, Recombinant, aa326-693, Human Fc-Tag, Strain 37997

Catalog No : USB-506231
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Product name Chikungunya Virus E2 Envelope Protein, Recombinant, aa326-693, Human Fc-Tag, Strain 37997
Catalog No USB-506231
Supplier’s Catalog No 506231
Supplier US Biologicals
Source antigen Recombinant, HEK293 cells
Reactivity
Cross reactivity
Applications
Molecular weight
Storage -70°C
Other names
Grade Highly Purified
Purity ~95% (Highly Purified)
Form Supplied as a liquid in 20mM HEPES, pH 7.0, 0.25% Triton X-100, 300mM sodium chloride.
Reactivity life 6 months
Note For reserch purpose only
Purity ~95% (Highly Purified)
Description Chikungunya virus is a member of the genus Alphavirus in the family Togaviridae. Chikungunya fever is a mosquito-borne disease first identified in Tanzania in 1953. Since 2004 there have been extensive outbreaks in Africa and Asia, and in 2013 the first cases were identified in the Caribbean, and by September 2014 more than 650,000 cases had been reported in the Americas. Chikungunya fever usually starts 2–4 days after chikungunya virus infection, with clinical symptoms including high fever, rash, headache, vomiting, myalgia, and severe joint pain. Because the virus is transmitted by the same mosquitos that transmit Dengue Virus and Zika Virus, and the clinical symptoms of infection with the viruses are also similar, it is important to be able to distinguish diagnostically between the different infections. Because the use of aspirin and other NSAIDs can increase the risk of haemmorhage in Dengue fever, patients should be treated as having Dengue fever until a diagnosis of Dengue fever has been excluded. It has been reported that E2 protein may offer higher sensitivity in serological assays when compared to E1 protein (Cho et al, 2008). Source: Recombinant protein corresponding to aa326-693 from Chikungunya Virus, fused to glycine-serine linker and human IgG1 Fc-Tag at C-terminal, expressed in HEK293 cells. Strain: Strain 37997 Recommended Dilution: Aliquot to avoid repeated freezing and thawing and store at -70°C. Aliquots are stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.