INSL5/INSL7, Recombinant, Human (Insulin-like Peptide INSL5, Insulin-like Peptide 5, UNQ156/PRO182/Relaxin-3, Insulin-like Peptide INSL7, Insulin-like Peptide 7, Prorelaxin H3, RLN3, RXN3, ZINS4, UNQ6188/PRO20213)
Catalog No : USB-143416
354.03€
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Product name | INSL5/INSL7, Recombinant, Human (Insulin-like Peptide INSL5, Insulin-like Peptide 5, UNQ156/PRO182/Relaxin-3, Insulin-like Peptide INSL7, Insulin-like Peptide 7, Prorelaxin H3, RLN3, RXN3, ZINS4, UNQ6188/PRO20213) | ||
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Catalog No | USB-143416 | ||
Supplier’s Catalog No | 143416 | ||
Supplier | US Biologicals | ||
Source antigen | Recombinant, E. coli | ||
Reactivity | |||
Cross reactivity | |||
Applications | |||
Molecular weight |
Storage | -20°C | ||
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Other names | |||
Grade | Highly Purified | ||
Purity | ≥98% by SDS-PAGE gel and HPLC analyses. | ||
Form | Supplied as a lyophilized powder. | ||
Reactivity life | 12 months | ||
Note | For reserch purpose only | ||
Purity | ≥98% by SDS-PAGE gel and HPLC analyses. | ||
Description | The Insulin/Relaxin structural family of proteins consists of at least seven members, each containing an Insulin-like hetero-dimeric structure consisting of two polypeptide chains held together by two inter-chain disulfide bonds. INSL7-INSL5 hybrid contains the B-chain of INSL7 (Relaxin-3), linked to the A-chain of INSL5. The INSL7-INSL5 hybrid protein can specifically activate the G protein coupled receptors, GPCR135 and GPCR142, but unlike Relaxin-3, does not induce significant activation of the LGR7 receptor. Recombinant INSL7-INSL5 hybrid is a hetero-dimeric 5.2kD protein consisting of a 27aa B-chaindisulfide linked to a 21aa A-chain. AA Sequence: A-chain: QDLQTLCCTD GCSMTDLSAL C B-chain: RAAPYGVRLC GREFIRAVIF TCGGSRW Quality Control: Verified by N-terminal and Mass Spectrometry analyses (when applicable). Endotoxin: <0.1ng/ug of protein (<1EU/ug). Protein Content: Verified by UV Spectroscopy and/or SDS-PAGE gel. Storage and Stability: Store lyophilized products at -20°C. For reconstituted solutions of most products, we recommend short-term storage at 4°C. For longer term storage the protein solution should be stored with a carrier protein (eg. 0.1% BSA) in working aliquots and stored frozen at -20°C. Additional freeze/thaw cycles may cause some denaturation of the protein. |
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