Relaxin-3, Recombinant, Human (H3 Relaxin, Insulin-like Peptide-7, INSL7)
Catalog No : USB-220223
432.20€
0.00€
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| Product name | Relaxin-3, Recombinant, Human (H3 Relaxin, Insulin-like Peptide-7, INSL7) | ||
|---|---|---|---|
| Catalog No | USB-220223 | ||
| Supplier’s Catalog No | 220223 | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, E. coli | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 5.5 | ||
| Storage | -20°C | ||
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| Other names | |||
| Grade | Highly Purified | ||
| Purity | ~98% (SDS-PAGE) | ||
| Form | Supplied as a lyophilized powder. No preservative added. Reconstitute with sterile ddH2O to 0.1-1mg/ml. | ||
| Reactivity life | 12 months | ||
| Note | For reserch purpose only | ||
| Purity | ~98% (SDS-PAGE) | ||
| Description | Relaxin-3 (H3 relaxin, Insulin-like peptide-7, INSL7) is a secreted protein structurally related to insulin, which is expressed primarily in the brain and central nervous system. Relaxin-3 has been identified as the ligand for the GPCR135 receptor, previously known as “somatostatin-like” or “angiotensin-like” peptide receptor, and also binds specifically to the LGR7 receptor, previously identified as an “orphan” G protein coupled receptor. Signaling by Relaxin-3 through its target receptors is, most likely, part of a CNS processing system, activated in response to signaling by neuropeptides and other factors. Intra cerebroventricular injections of Relaxin-3 have been shown to cause a significant increase of food intake and body weight in Wistar rats. Recombinant Relaxin-3 is a disulfide linked heterodimeric protein consisting of a 24aa A-chain and a 27aa B-chain. Source: Recombinant protein corresponding to human Relaxin-3, expressed in E. coli. Molecular Weight: ~5.5kD Endotoxin: <0.1ng/ug of protein (<1EU/ug) AA Sequence: A Chain: DVLAGLSSSC CKWGCSKSEI SSLC B Chain: RAAPYGVRLC GREFIRAVIF TCGGSRW Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
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