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Categories: Peptides & Proteins / Proteins

Product name			CLIC2, Recombinant, Human, aa1-247, His-Tag (Chloride intracellular channel protein 2)
Catalog No			USB-349796
Supplier’s Catalog No			349796
Supplier			US Biologicals
Source antigen			Recombinant, E. coli
Reactivity
Cross reactivity
Applications
Molecular weight			30.5

Storage			-20°C
Other names
Grade			Highly Purified
Purity			~95% (SDS-PAGE)
Form			Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 0.1M sodium chloride, 1mM DTT, 20% glycerol.
Reactivity life			6 months
Note			For reserch purpose only
Purity			~95% (SDS-PAGE)
Description			CLIC2, also known as chloride intracellular channel protein 2, regulates cellular traffic of chloride ions, a critical component of all living cells. This protein is involved in membrane potential stabilization, signal transduction, cell volume regulation and organic solute transport. It is detected in fetal liver and adult skeletal muscle tissue. It is a potential candidate for one of the many diseases linked to Xq28. Source: Recombinant protein corresponding to aa1-247 of human CLIC2, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~30.5kD AA Sequence: MGSSHHHHHH SSGLVPRGSH MSGLRPGTQV DPEIELFVKA GSDGESIGNC PFCQRLFMIL WLKGVKFNVT TVDMTRKPEE LKDLAPGTNP PFLVYNKELK TDFIKIEEFL EQTLAPPRYP HLSPKYKESF DVGCNLFAKF SAYIKNTQKE ANKNFEKSLL KEFKRLDDYL NTPLLDEIDP DSAEEPPVSR RLFLDGDQLT LADCSLLPKL NIIKVAAKKY RDFDIPAEFS GVWRYLHNAY AREEFTHTCP EDKEIENTYA NVAKQKS Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.