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Categories: Peptides & Proteins / Proteins

Product name			KLK15, Recombinant, Human, aa22-256, His-Tag (Kallikrein-15 Isoform 4 Preproprotein)
Catalog No			USB-218293
Supplier’s Catalog No			218293
Supplier			US Biologicals
Source antigen			Recombinant, E. coli
Reactivity
Cross reactivity
Applications
Molecular weight			28.2

Storage			-20°C
Other names
Grade			Purified
Purity			~90% (SDS-PAGE)
Form			Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 0.4M urea, 10% glycerol.
Reactivity life			6 months
Note			For reserch purpose only
Purity			~90% (SDS-PAGE)
Description			Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK15 is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In prostate cancer, it has increased expression, which indicates its possible use as a diagnostic or prognostic marker for prostate cancer. KLK15 contains multiple polyadenylation sites and alternative splicing results in multiple transcript variants encoding distinct isoforms. Source: Recombinant corresponding to aa22-256 from human KLK15 protein, fused to His-tag at N-terminus, expressed in E.coli. Molecular Weight: ~28.2kD (258aa) Applications: Suitable for use in SDS-PAGE. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.