KLK3, Recombinant, Human (Kallikrein-3, APS, KLK2A1, PSA, Hk3, Prostate-Specific Antigen, Gamma-Seminoprotein, Kallikrein-related Peptidase 3, Semenogelase)
Catalog No : USB-219996
1200.03€
0.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Product name | KLK3, Recombinant, Human (Kallikrein-3, APS, KLK2A1, PSA, Hk3, Prostate-Specific Antigen, Gamma-Seminoprotein, Kallikrein-related Peptidase 3, Semenogelase) | ||
|---|---|---|---|
| Catalog No | USB-219996 | ||
| Supplier’s Catalog No | 219996 | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, Human | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 26.2 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | |||
| Grade | Highly Purified | ||
| Purity | ~95% (SDS-PAGE) | ||
| Form | Supplied as a lyophilized powder in PBS, pH 7.4. No preservative added. | ||
| Reactivity life | 12 months | ||
| Note | For reserch purpose only | ||
| Purity | ~95% (SDS-PAGE) | ||
| Description | Prostate-specific antigen, also known as Gamma-seminoprotein, Kallikrein-3, kallikrein-related peptidase 3, Semenogelase, KLK3 and PSA, is a secreted protein which belongs to thepeptidase S1 family and Kallikrein subfamily. KLK3/Kallikrein 3 contains one peptidase S1 domain. KLK3/Kallikrein 3 is a glycoprotein produced almost exclusively by the prostate gland. KLK3/Kallikrein 3 is produced for the ejaculate where it liquifies the semen in the seminal coagulum and allows sperm to swim freely.It is also believed to be instrumental in dissolving the cervical mucous, allowing the entry of sperm. Human KLK3/Kallikrein 3 and human KLK2 are closely related products of the human kallikrein genes KLK3 and KLK2, respectively. Both KLK3/Kallikrein 3 and human kallikrein 2 are produced and secreted in the prostate and have important applications in the diagnosis of prostate cancer. Understanding the mechanism by which genetic variation in KLK3/Kallikrein 3 affects prostate cancer risk has important implications for study of the biological role of KLK3/Kallikrein 3 in prostate tumorigenesis. Source: Recombinant protein corresponding to human KLK3, expressed in Human Molecular Weight: ~26.2kD Biological Activity: Measured by its ability to cleave the colorimetric peptide substrate, Succinyl-Arg-Pro-Tyr-p-Nitroanilide (Suc-RPY-pNA). The specific activity is >100pmoles/min/ug. Endotoxin: <0.1EU/ug purified protein Storage and Stability: Lyophilized powder may be stored at -70°C. Reconstitute with sterile ddH2O or PBS. Aliquot to avoid repeated freezing and thawing. Store at -70°C. Reconstituted product is stable for 6 months at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
Product Details
© 2020 Imugex All Rights Reserved