Prekallikrein, Human (Fletcher Factor, Kininogenin)

Catalog No : USB-301269
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Product name Prekallikrein, Human (Fletcher Factor, Kininogenin)
Catalog No USB-301269
Supplier’s Catalog No 301269
Supplier US Biologicals
Source antigen Human Plasma
Reactivity
Cross reactivity
Applications
Molecular weight 86
Storage -70°C
Other names
Grade Highly Purified
Purity ~95% (SDS-PAGE)
Form Supplied as a liquid in 4mM sodium acetate-HCl, 0.15M sodium chloride, pH 5.3.
Reactivity life 12 months
Note For reserch purpose only
Purity ~95% (SDS-PAGE)
Description Prekallikrein is the glycosylated single chain zymogen precursor of the plasma serine protease kallikrein. Plasma prekallikrein circulates with kininogen and is activated by Factor XIIa in the intrinsic coagulation pathway. Kallikrein activates plasminogen in fibrinolysis and cleaves kininogen in the bradykinin system of vasodilation. Prekallikrein deficiency is rare and causes increased activated partial thromboplastin time. Elevated plasma prekallikrein is associated with diabetes and cardiovascular disease. Source: Prekallikrein, from Human Plasma Molecular Weight: ~86kD Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.